ARPHA Preprints, doi: 10.3897/arphapreprints.e108755
The energy-rush and insulin model of obesity
expand article infoHangxing Jia
‡ Key Laboratory of Zoological Systematics and Evolution & State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
Open Access
Abstract

Obesity has been a global health problem since the 1980s. Despite the intensive research, there is no scientific consensus on the onset of obesity. The energy balance model (EBM) and the carbohydrate-insulin model (CIM) are two competing obesity theories, each with supporting and conflicting evidence. In this essay, I propose a new model, the energy-rush and insulin model (ERIM) which integrates not only the energy intake and expenditure but also the food composition and digestibility, to explain how the high energy-rush and insulin secretion contribute to the development of obesity. The ERIM offers a novel framework to explain how obesity occurs and proposes new recommendations for obesity management which may reverse the obesity epidemic In the future.

Keywords
EBM, CIM, ERIM, energy-rush, insulin secretion, obesity, food digestibility, GLP-1