Priscila Gil‡Corresponding author: Priscila Gil ( priscila.gil83@gmail.com ) © Priscila Gil. This is an open access preprint distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Citation:
Gil P (2025) Strategic Proposal for Selective Awakening and Targeted Elimination of Latent Viruses Through Molecular Pathway Disruption. ARPHA Preprints. https://doi.org/10.3897/arphapreprints.e165146 |  |
Latent viral infections, such as those caused by Herpes Simplex Virus (HSV), Human Immunodeficiency Virus (HIV), and Epstein-Barr Virus (EBV), remain a major obstacle to achieving complete viral eradication. These pathogens establish dormancy within host cells, effectively evading immune detection and undermining standard antiviral therapies. This research proposal outlines a three-phase strategy that integrates nanotechnology and molecular biology to selectively reactivate latent viruses and eliminate them through targeted capture and neutralization mechanisms. By employing biomimetic nanostructures and phase-specific activation triggers, this approach seeks to minimize off-target effects and collateral damage, offering a controlled and replicable platform for treating chronic viral infections.